Microdosing GLP-1s and Diet-Culture Flashbacks

I read the Vogue article about celebrities and microdosing GLP-1 medications (Ozempic, Zepbound, Mounjaro) and immediately flashed back to my diet-culture days. Growing up in the ’90s and early 2000s, I tried everything from Weight Watchers to MyFitnessPal, meticulously tracking points, counting calories, and stressing over “too-heavy” salad dressings. It feels wild to think how much has changed… and how much hasn’t.

For a little context, these drugs are synthetic versions of a hormone our bodies produce naturally called GLP-1, which helps regulate glucose, slow digestion, reduce cravings, and make us feel full. They’re usually prescribed for diabetes or obesity, but lately, they’ve become a bit of a celebrity trend: Serena Williams, Oprah, Kelly Clarkson, and Andy Cohen have all talked about taking them. Last year, one in eight Americans reported trying a GLP-1 medication, mostly for the weight-loss side effect.

Microdosing, as explained by Dr. Rocio Salas-Whalen, a board-certified physician specializing in obesity and endocrinology, is taking a smaller dose than the FDA-approved amount. People try it to avoid side effects like nausea, fatigue, or the infamous “Ozempic face.” Dr. Salas-Whalen points out that microdosing doesn’t always give the full benefits, but for some, it can be a maintenance-level option under careful supervision.

Reading all this made me think about the girl I used to be: the one who counted points, felt guilty after meals, and lived in her head about every bite. That girl would have been fascinated by a hormone that curbs cravings. Now, decades later, I can approach food and my body with curiosity and gratitude — listening to hunger cues, enjoying meals without guilt, and celebrating everything my body has carried me through. I no longer chase numbers or extremes, but I can see that these tools exist for a reason, and used thoughtfully, they're just another way to show up for yourself.

Ask Clara: What are the benefits of GLP-1s for women?